Sialometric and Sialochemical Changes in Morbidly Obese Patients before and after Bariatric Surgery.

AIM: To evaluate the sialometric and sialochemical changes in morbidly obese patients before and after bariatric surgery. MATERIALS AND METHODS: A total of 74 participants were divided into three groups paired by sex and age: (a) Experimental 1 (E1)-morbid obesity (n = 40)-according to the Fobi-Capella technique, corresponding to the individuals with a body mass index (BMI) of greater than 40 kg/m2 prior to bariatric surgery; (b) Experimental 2 (E2)-the same individuals after surgery; and (c) control (C) (n = 34)-individuals with a BMI of nearly 23 kg/m2. The measure of salivary flow was carried out by collecting stimulated saliva. The pH was evaluated using the pocket pH meter, while the salivary buffer capacity (SBC) was determined by the titration method. Analyses of the salivary concentration of total proteins (TPs), amylase activity, urea, calcium (Ca++), and glucose were evaluated using the calorimetric method. RESULTS: Group E1, as compared with group C, presented the highest pH levels (p = 0.03), amylase activity (p = 0.00), and calcium (p = 0.00). The opposite was observed for glucose (p = 0.00), TP (p = 0.04), and urea (p = 0.04). Group E2, as compared with group C, revealed higher levels of amylase (p = 0.00) and calcium (p = 0.00). The opposite was observed for SBC (p = 0.01), PT (p = 0.00), and glucose (p = 0.00). Group E1, as compared with group E2, presented higher values of SBC (p = 0.00) and urea (p = 0.00). The lowest values were found for calcium and urea (p = 0.03). CONCLUSION: Both weight gain and bariatric surgery are risk factors for the oral condition, causing change in some important salivary components, such as TP, amylase, calcium, and glucose. CLINICAL SIGNIFICANCE: This article is a valuable addition to the scientific literature, due to its novelty. There are no papers that show salivary alterations related to bariatric surgeries.

Inflammatory pseudotumor of the spleen concomitant with renal cell carcinoma: case report.

CONTEXT: Inflammatory pseudotumor is a rare benign lesion that can occur at a wide variety of primary sites. It is usually worrisome for the patient and the medical staff, since it cannot be clinically or radiologically distinguished from malignant entities. CASE REPORT: We report on a case of splenic inflammatory pseudotumor presenting with concomitant renal cell carcinoma. Despite the alarming macroscopic appearance of pseudotumors, their microscopic features usually confirm the inflammatory nature of such lesions. Evidence regarding the etiology of pseudotumors is still lacking, but hypotheses have been created.

Doença celíaca: uma visäo atual / Celiac disease: an actual vision

A Doença Celíaca (DC) consiste em uma intolerância permanente al glúten em indivíduos susceptíveis e é uma das causas mais comuns de diarréia crônica e déficit de crescimento na infância. Até recentemente seu diagnóstico baseava-se apenas em critérios clínicos e histológicos. Embora a histologia de intestino delgado permaneça o "o gold standard" para o diagnóstico de DC, testes de screening sorológico, simples, confiáveis e näo invasivos tem sido utilizados . Anticorpos anti-gliadina (AGA), anti-reticulina (ARA) e anti-endomísio (EMA) säo encontrados em amostras de soros de pacientes com DC. Os EMA tem evidenciado um alto grau de especificidade e sensibilidade nas várias fases das enteropatias por sensibilidade ao glúten, representando um excelente teste para o diagnóstico e seguimento de DC, bem como para a identificaçäo de suas formas silenciosas e latentes